Located by the Catholic University of Lublin, the Holy Cross church was founded in the fourteenth century. The creation of the church is associated with a legend according to which the Gdańsk merchant Henry tried to steal the relics of the Holy Cross, kept in the Dominican church. Under cover of the night, he wanted to take the relics out of Lublin, but outside the city walls the oxen stopped and did not want to pull the cariage anymore. Terrified, Henry turned the carriage back to the city, returned the relics, and founded a church at the place of the miraculous event - originally wooden, later bricked, in the Renaissance style.

At the end of the 17th century, the temple was taken over by a branch of the Dominican Order, and a monastery was built next to the church. In the nineteenth century, the church was used, among others, as a barracks warehouse, and its state gradually deteriorated. At the times of the Second Polish Republic, during the reconstruction associated with the adaptation of the entire complex to the needs of a university, the temple was renovated with partial preservation of the Renaissance features of the building's form, while the interior acquired the harsh atmosphere of the temples of the first centuries of Christianity.